Hispolon Protects against Acute Liver Damage in the Rat by Inhibiting Lipid Peroxidation, Proinflammatory Cytokine, and Oxidative Stress and Downregulating the Expressions of iNOS, COX-2, and MMP-9
Figure 2
Effect of hispolon on the activities of serum AST and ALT in CCl4-injected rats. Animals were i.p. treated with hispolon (5, 10, and 20 mg/kg) once daily for consecutive seven days. One hour after the final hispolon treatment, the rats were injected with CCl4 (1.5 mL/kg, i.p.). The rats were killed 24 h after the CCl4 injection. Hepatotoxicity was determined by quantifying the serum activities of aspartate aminotransferase (AST) and alanine aminotransferase (ALT). The values are reported as the mean ± S.D. of six rats per group. ### compared with control; *** compared with the CCl4 group.
