Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression

Figure 3

KGBE inhibits the production of inflammatory mediators in HFD-fed ApoE^−/− mice. (a–c, upper panels) Levels of TNF-α, IL-1β, and iNOS mRNAs were determined in the aortic tissues from mice fed NCD, HFD, and HFD supplemented with KGBE or KRGE for 16 weeks by RT-PCR. (a–c, lower panels) Levels of TNF-α, IL-1β, and NOx were determined in sera from mice using ELISA kits and a reductase-based Griess reaction kit. Data shown in graphs are the mean ± S.D. (𝑛=8). *𝑃<0.05 and **𝑃<0.01 versus HFD.

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