Effects and Interaction of Icariin, Curculigoside, and Berberine in Er-Xian Decoction, a Traditional Chinese Medicinal Formula, on Osteoclastic Bone Resorption
Figure 6
Effects of I, C, B, and their combination on RANKL-induced signaling pathways. Osteoclasts induced from bone marrow cells by M-CSF and RANKL were treated for 24 h and assessed for phosphorylation of JNK, ERK, p38 MAPK, and Akt and the degradation of IκBα by Western blot. β-actin was used as an internal reference.
