Evidence-Based Complementary and Alternative Medicine

Research Article

Therapeutic Effects of Cortex acanthopanacis Aqueous Extract on Bone Metabolism of Ovariectomized Rats

Table 3

Effects of 12-week treatment with Cortex acanthopanacis extract (CAE) on the bone mineral density (BMD), the bone volume (BV/TV), the mineralizing surface (MS/BS), the eroded surface (ES/BS), the mineral apposition rate (MAR), and the osteoid thickness (O.Th) of tibia from rats.
GroupnBMD (g/cm2)BV/TV (%)ES/BS (%)MS/BS (%)MAR ( 𝜇 m/d)O.Th ( 𝜇 m)
NC12 0 . 3 0 8 ± 0 . 0 0 8 2 8 . 0 8 ± 7 . 2 6 3 . 5 6 ± 1 . 4 7 8 . 2 3 ± 2 . 6 9 1 . 3 0 ± 0 . 1 8 5 . 6 5 ± 1 . 3 4
Sham12 0 . 3 0 4 ± 0 . 0 0 7 2 7 . 1 8 ± 8 . 7 8 3 . 4 0 ± 1 . 5 4 7 . 4 0 ± 2 . 4 1 1 . 3 8 ± 0 . 1 6 6 . 2 0 ± 1 . 2 9
OVX12 0 . 1 7 9 ± 0 . 0 0 7 a 8 . 9 5 ± 3 . 0 4 a 9 . 3 1 ± 2 . 2 2 a 1 4 . 5 4 ± 3 . 3 1 a 1 . 8 6 ± 0 . 2 3 a 7 . 7 7 ± 1 . 6 4 b
E212 0 . 2 9 8 ± 0 . 0 0 6 c 2 3 . 6 1 ± 4 . 7 1 c 3 . 2 8 ± 1 . 3 1 c 7 . 7 2 ± 2 . 6 6 c 1 . 3 2 ± 0 . 2 2c 6 . 3 7 ± 1 . 4 2 d
FEE12 0 . 2 7 1 ± 0 . 0 0 7 c 2 0 . 9 6 ± 4 . 7 8 c 4 . 3 9 ± 1 . 3 8 c 9 . 2 6 ± 2 . 7 5 c 1 . 4 5 ± 0 . 1 9 c 6 . 4 9 ± 1 . 1 1 d
CAE12 0 . 2 3 9 ± 0 . 0 0 8 d 1 6 . 4 2 ± 4 . 0 5 c 5 . 1 8 ± 1 . 1 6 c 1 3 . 0 6 ± 3 . 7 0 1 . 7 4 ± 0 . 3 3 7 . 4 5 ± 1 . 4 3
Results are expressed as mean ± SD.
a 𝑃 < 0 . 0 1 against Sham group (rats with Sham operation).
b 𝑃 < 0 . 0 5 against Sham group.
c 𝑃 < 0 . 0 1 against OVX group (ovariectomized rats).
d 𝑃 < 0 . 0 5 against OVX group.