The Molecular Basis of Wound Healing Processes Induced by Lithospermi Radix: A Proteomics and Biochemical Analysis
Figure 7
SD rat experiment to verify the efficacy of the LR extracts in wound healing. The diameter of the wounds was used as a guideline for the rate of wound healing. Two wound circles were generated on the back of SD rats using an 8 mm biopsy punch. DMSO, LR5, and LR20 were used to treat the wounds and the diameter of the wounds was measured twice per day. It was found that the efficacy of wound closing rate of the wounds after LR5 and LR20 treatments was far much greater that when the wounds were treated with DMSO only (a). The wound healing rate was also recorded by digital camera at interval of 4 days (b). This demonstrated that the wound started to shrink after 2 days and continued to shrink further until 11 days. It is worth noting that wounds treated with LR20 showed the fastest wound closing rate compared to the other treatments (b). Results are triplicates and are presented as means ± SD (). *; **.
