Scutellaria baicalensis Extracts and Flavonoids Protect Rat L6 Cells from Antimycin A-Induced Mitochondrial Dysfunction
Figure 2
Effects of extracts on total cellular ATP levels and ADP/ATP ratio. (a) Total ATP levels in L6 cells treated with AMA. Cells were pretreated with baicalein, baicalin, or wogonin (each at 50 μg/mL) for 1 h. Cells were pretreated with extracts (50, 100, 200 μg/mL each) for 1 h, and then 100 μg/mL of AMA was added. ATP levels were measured using the ATP Lite luminescence-based assay in which results are reported as a percentage of the control. (b) ADP/ATP ratio in L6 cells was determined using the EnzyLight ADP/ATP ratio assay kit. Data were expressed as a percentage of control. *.
