Treatment with Ginger Ameliorates Fructose-Induced Fatty Liver and Hypertriglyceridemia in Rats: Modulation of the Hepatic Carbohydrate Response Element-Binding Protein-Mediated Pathway
Figure 7
Hepatic mRNA expression of peroxisome proliferator-activated receptor-(PPAR-) α (a), carnitine palmitoyltransferase (CPT)1a (b), acyl-CoA oxidase (ACO) (c), and CD36 (d) in water-control, 10% fructose solution-control, and fructose pair-fed ginger-treated rats at week 5. Animals were coadministered with ginger extract (50 mg/kg/day) or vehicle (ginger: 0 mg/kg, 5% Gum Arabic) by oral gavage daily for 5 weeks. mRNA was determined by real-time PCR. Data are means ± SEM ( each group). .
