Ferulsinaic Acid Modulates SOD, GSH, and Antioxidant Enzymes in Diabetic Kidney

Table 3

(a) Effect of FA on carrageenan-induced rat paw edema

Treatment	Thickness of the injected foot, mm
	3 h	5 h
Olive oil	5.1±0.12	5.03±0.14
Indomethacin 10 mg/kg	1.68±0.15(62%)^∗∗	1.51±0.10(70%)^∗∗
FA, 5 ng/kg	3.16±0.21(38%)^∗	3.05±0.09(39%)^∗
FA, 50 ng/kg	2.95±0.13(42%)^∗∗	2.81±0.17(44%)^∗∗
FA, 500 ng/kg	2.18±0.21(57%)^∗∗	2.05±0.15(59%)^∗∗

(b) Effect of FA on dextran-induced rat paw edema

Treatment	Thickness of the injected foot, mm
	45 min	90 min
Olive oil	6.10±0.17	5.90±0.17
Indomethacin, 10 mg/kg	1.95±0.15(68%)^∗∗	1.66±0.10(72%)^∗∗
FA, 5 ng/kg	3.52±0.16(42%)^∗	3.1±0.09(47%)^∗
FA, 50 ng/kg	3.1±0.21(49%)^∗∗	2.75±0.17(53%)^∗∗
FA, 500 ng/kg	2.65±0.12(57%)^∗∗	2.25±0.15(62%)^∗∗

Values are mean ± SE, 𝑛=6, ^∗𝑃<0.05, ^∗∗𝑃<0.001 compared with control, post-hoc test. Values given in parentheses represent percentage of inhibition.