Evidence-Based Complementary and Alternative Medicine

Research Article

Ameliorative Effects of Scopoletin from Crossostephium chinensis against Inflammation Pain and Its Mechanisms in Mice

Table 1

Effects of scopoletin and indomethacin (Indo) on changes in CAT, SOD, and GPx activities were studied in Carr-induced paw edema (5th hr) in mice.
GroupsCAT
(U/mg protein)		SOD
(U/mg protein)		GPx
(U/mg protein)
Control 5 . 4 8 ± 0 . 0 8 4 . 8 9 ± 0 . 0 8 1 2 . 8 7 ± 0 . 1 1
Carr 3 . 3 4 ± 0 . 1 2 ### 2 . 1 6 ± 0 . 0 4 ### 7 . 0 7 ± 0 . 1 2 ###
Carr + Indo 4 . 9 6 ± 0 . 1 1 ** 4 . 2 3 ± 0 . 0 6 ** 1 0 . 5 6 ± 0 . 2 9 **
Carr + scopoletin
(1 mg/Kg)		 3 . 9 4 ± 0 . 0 5 * 3 . 3 5 ± 0 . 1 1 * 8 . 7 4 ± 0 . 0 9 *
Carr + scopoletin
(5 mg/Kg)		 4 . 7 4 ± 0 . 0 6 ** 3 . 8 2 ± 0 . 0 7 ** 1 0 . 1 9 ± 0 . 1 3 **
Carr + scopoletin
(10 mg/Kg)		 5 . 1 3 ± 0 . 1 4 *** 4 . 6 1 ± 0 . 0 3 *** 1 1 . 6 4 ± 0 . 1 0 ***
Each point represents the average value for three individual animals. Each value represents as mean ± S.E.M. ### 𝑃 < 0 . 0 0 1 as compared with the control. * 𝑃 < 0 . 0 5 , ** 𝑃 < 0 . 0 1 , and *** 𝑃 < 0 . 0 0 1 as compared with the Carr group (one-way ANOVA followed by Scheffe’s multiple range test).