Different Effects of Resveratrol on Dose-Related Doxorubicin-Induced Heart and Liver Toxicity

Table 1

Serum and plasma markers of heart and liver damage (M ± SD).

	FABP (𝜇g/L)	BNP (𝜇g/L)	AST (IU/L)	ALT (IU/L)	CK (IU/L)	LDH (IU/L)	ALP (IU/L)
Control	5.0±1.59	0.40±0.237	104.3±9.07	57.63±7.11	1536.75±343.61	1275.9±596.29	186.25±31.62
1DOX	7.0±1.97	0.54±0.437	96.0±9.03	68.20±13.65	1099.00±421.51	647.8±179.96	89.80±28.86^a
1DOX + RV	5.6±0.76	0.52±0.672	130.8±42.49	100.00±23.05^a	981.80±377.63^a	979.2±85.56	91.60±19.76^a
2DOX	11.1±3.26^a	1.32±0.759^a	91.4±45.88	48.80±27.69	953.40±142.70^a	519.2±151.58^a	84.20±20.09^a
2DOX + RV	4.6±2.11^b	0.16±0.257^b	69.6±18.72^a	30.00±19.44^a	545.63±368.32^a	567.3±211.00^a	74.63±33.58^a

^a𝑃≤0.05 versus control. ^b𝑃≤0.05 versus DOX.