Effects of 12-Week Bacopa monnieri Consumption on Attention, Cognitive Processing, Working Memory, and Functions of Both Cholinergic and Monoaminergic Systems in Healthy Elderly Volunteers

Table 2

The effect of repetitive administration of B. monnieri on event-related potential. Data are presented as mean ± SD. (𝑛=20/group).

Wave	Group	Baseline	4-week	8-week	12-week	Delay
N100 latency	Placebo	103.6±5.62	103.45±4.58	103.15±2.10	103.45±4.09	103.55±3.74
	300 mg	103.25±3.30	101.05±3.96	101.35±3.36	99.65±3.29 ***	100.35±3.68
	600 mg	103.85±2.9	102.05±2.89	102.25±2.29	100.8±2.62 *	102.75±3.98
		F(2, 57)   =  0.03,  P  =  0.969	F(2, 57)  =  1.26,  P  =  0.291	F(2, 57)  =  2.31,  P =  0.108	F(2, 57)  =  6.63, P  =  0.003	F(2, 57)  =  3.82,  P  =  0.028
N100 amplitude	Placebo	7.85±3.75	7.9±3.12	7.85±3.67	7.7±3.06	7.75±4.05
	300 mg	7.65±3.71	8.1±3.74	8.5±3.71	8.64±3.15	8.5±3.36
	600 mg	7.55±3.69	7.73±4.10	8.1±3.88	8.11±3.04	7.8±3.56
		F(2, 57)   =  0.034,  P  =  0.97	F(2, 57)  =  0.060,  P  =  0.94	F(2, 57)  =  0.136,  P =  0.873	F(2, 57)  =  0.344, P  =  0.711	F(2, 57)  =  0.261,  P  =  0.771
P300 latency	Placebo	326±8.33	326.55±10.01	326 ± 5.71	326.15±4.63	326.00±10.61
	300 mg	326.4±5.68	323.8±5.50	321.3±5.89 *	319.9±4.65 **	324.55±6.12
	600 mg	326.2±8.41	324.45±8.07	321.2±8.52	320.65±7.30 *	326.85±7.47
		F(2, 57)   =  0.004,  P  =  0.99	F(2, 57)  =  0.633,  P  =  0.53	F(2, 57)  =  3.223,  P =  0.047	F(2, 57)  =  7.235, P  =  0.002	F(2, 57)  =  0.394,  P  =  0.677
P300 amplitude	Placebo	10.4±6.80	10.6±6.51	10.55±4.72	10.55±6.10	10.5±3.39
	300 mg	10.3±4.06	11.7±6.06	12.75±5.91	12.75±5.75	12.45±6.47
	600 mg	10.45±4.63	10.85±5.44	11±5.69	11.1±4.55	10.95±5.08
		F(2, 57)   =  0.004,  P  =  0.99	F(2, 57)  =  0.183,  P  =  0.83	F(2, 57)  =  0.902,  P =  0.411	F(2, 57)  =  0.863, P  =  0.428	F(2, 57)  =  0.789,  P  =  0.459