A Pilot Study for the Neuroprotective Effect of Gongjin-dan on Transient Middle Cerebral Artery Occlusion-Induced Ischemic Rat Brain
Figure 3
Quantitative analysis of immunoreactivities of GFAP, NeuN, and OX-42 at days on peri-infarct area after MCAo. Histological analysis was shown into GFAP, NeuN, OX-42 staining at 14 days after MCAo. Quantitative immunoreactivities for groups are shown as bar graphs on the right side of each panel. The expression of GFAP in gongjin-dan group was significantly decreased compared with control group. NeuN-positive cells also showed difference in the control group. There were many NeuN-positive cells in gongjin-dan group compared to control group. The expression of OX-42 in gongjin-dan group was significantly decreased compared with control group. In the gongjin-dan, the number of activated microglial cells was decreased and the number of neuronal cells was increased in the peri-infarct area. Data are expressed as mean ± SD, *.
