Gallic Acid Attenuates Platelet Activation and Platelet-Leukocyte Aggregation: Involving Pathways of Akt and GSK3<i>β</i>

<table>Flow cytometric analysis of the effects of gallic acid on platelet-leukocyte aggregates (PLAs) after stimulation with ADP or U46619. Quantitative results of the influence of gallic acid (100 <i>μ</i>M, 500 <i>μ</i>M) on PLA induced by (a) ADP (2 <i>μ</i>M) or (b) U46619 (2 <i>μ</i>M) by means of the mean fluorescence intensity of CD42a. Platelet-monocyte (open bars) and platelet-granulocyte (filled bars) aggregates were both inhibited by gallic acid in a concentration-dependent manner. Results are presented as mean ± SEM, <svg height="10.925" id="M2" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 10.925" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus control samples stimulated with ADP or U46619. GA: gallic acid.</table>

Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Gallic Acid Attenuates Platelet Activation and Platelet-Leukocyte Aggregation: Involving Pathways of Akt and GSK3<i>β</i> 

Evidence-Based Complementary and Alternative Medicine

Gallic Acid Attenuates Platelet Activation and Platelet-Leukocyte Aggregation: Involving Pathways of Akt and GSK3β

Figure 2