In Vitro Screening of Medicinal Plants Used in Mexico as Antidiabetics with Glucosidase and Lipase Inhibitory Activities
Table 1
Alpha-glucosidase and lipase inhibition of 23 medicinal plants used in Mexico for diabetes trearment.
Scientific name
Local name
Yield %
glucosidase % inhibitiona
Lipase % inhibitionb
Acacia farnesiana (L.) Willd.
Huizache
19.0
Achillea millefolium L.
Milenrama
27.3
Annona squamosa L.
Anona
16.4
Artemisia absinthium L.
Ajenjo
15.5
Bidens pilosa L.
Aceitilla
16.2
Calea ternifolia Kunth
Prodigiosa
18.4
Camellia sinensis (L.) Kuntze
Te Verde
35.5
Cecropia obtusifolia Bertol.
Guarumbo
18.6
Hintonia latiflora (Sessé & Moc. ex DC.) Bullock
Copalchi
41.3
Crataegus mexicana Moc. & Sessé ex DC.
Tejocote
27.5
ppt
Eucalyptus globulus Labill.
Eucalipto
22.5
Guazuma ulmifolia Lam.
Guacima
15.4
Iostephane heterophylla (Cav.) Benth.
Zacapal
24.3
Justicia spicigera Schltdl.
Muicle
22.1
Lepidium virginicum L.
Lentejita
17.4
Ludwigia octovalvis (Jacq.) P.H.Raven
Clavillo
37.0
Marrubium vulgare L.
Marrubio
19.4
Persea americana Mill.
Aguacate
27.8
Piper sanctum Miq.
Hoja santa
22.2
15.1±2.2
Psidium guajava L.
Guayaba
24.5
ppt
Ricinus communis L.
Higuerilla
24.3
Tamarindus indica L.
Tamarindo
18.8
ppt
Taraxacum officinale Webb
Diente de León
22.1
Tecoma stans (L.) Juss. ex Kunth
Tronadora
25.6
a
Percentage of -glucosidase inhibition was calculated at = 10 min, whereby the reaction = (mean free glucose in sample/mean free glucose in uninhibited control) × 100.
b
Percentage of lipase inhibition was calculated using the slope at = 2–5 min, whereby the reaction = (mean slope in sample/mean slope in uninhibited control) × 100. ppt: sample precipitation strongly interfered with lipase assay.
