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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 702857, 15 pages
http://dx.doi.org/10.1155/2012/702857
Research Article

Inhibition of Cell Growth and Induction of Apoptosis by Antrodia camphorata in HER-2/neu-Overexpressing Breast Cancer Cells through the Induction of ROS, Depletion of HER-2/neu, and Disruption of the PI3K/Akt Signaling Pathway

1Department of Health and Nutrition Biotechnology, Asia University, Taichung 41354, Taiwan
2Institute of Nutrition, China Medical University, Taichung 40402, Taiwan
3Department of Life Sciences, China Medical University, Taichung 40402, Taiwan
4Department of Cosmeceutics, College of Pharmacy, China Medical University, Taichung 40402, Taiwan
5Department of Medical Research, Chi-Mei Medical Center, Tainan 71079, Taiwan
6Institute of Biochemistry and Biotechnology, Chung Shan Medical University, Taichung 40402, Taiwan
7Department of Life Sciences, National Central University, Chung Li 32001, Taiwan

Received 16 February 2012; Accepted 2 April 2012

Academic Editor: Raffaele Capasso

Copyright © 2012 Chuan-Chen Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Chuan-Chen Lee, Hsin-Ling Yang, Tzong-Der Way, et al., “Inhibition of Cell Growth and Induction of Apoptosis by Antrodia camphorata in HER-2/neu-Overexpressing Breast Cancer Cells through the Induction of ROS, Depletion of HER-2/neu, and Disruption of the PI3K/Akt Signaling Pathway,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 702857, 15 pages, 2012. https://doi.org/10.1155/2012/702857.