Chinese Patent Medicine Liu Wei Di Huang Wan Combined with Antihypertensive Drugs, a New Integrative Medicine Therapy, for the Treatment of Essential Hypertension: A Systematic Review of Randomized Controlled Trials

Table 1

Characteristics and methodological quality of the included studies.

Study ID	Sample	Diagnosis standard	Intervention	Control	Course (week)	Outcome measure
Cai 2004 [18]	162	1999 WHO—ISH GMH	LWDHW plus sustained-release nifedipine	sustained-release nifedipine	8	BP
Zhang 2007 [19]	68	Hypertension diagnostic criteria (unclear)	LWDHW plus nifedipine controlled release tablet	Nifedipine controlled release tablet	4	BP
Chen et al. 2008 [20]	97	CGMH-2005	LWDHW plus captopril	captopril	8	BP; adverse effect
Zhang et al. 2004 [21]	78	1993 WHO—ISH GMH	LWDHW plus enalapril	enalapril	7	BP; TCM-SSD
Zhou et al. 2003 [22]	100	1999 WHO—ISH GMH	LWDHW plus nifedipine controlled release tablet	Nifedipine controlled release tablet	18	BP; TCM-SSD
Hu et al. 1994 [23]	50	Hypertension diagnostic criteria (unclear); TCM diagnostic criteria (unclear)	LWDHW plus nifedipine	nifedipine	10	BP