Effect of Human Placental Extract on Health Status in Elderly Koreans

Table 1

Comparison of clinical and biochemical characteristics between the two study groups at baseline.

	Placebo (𝑛=17)	HPE (𝑛=22)	P value
Male patient, no. (%)	9 (52.9)	10 (45.5)	0.643
DM, no. (%)	2 (11.8)	4 (18.2)	0.679*
HTN, no. (%)	7 (41.2)	14 (63.6)	0.163
Hyperlipidemia, no. (%)	3 (17.6)	3 (13.6)	1.000*
Age (years)	69.1±3.5	68.0±2.4	0.353
Weight (kg)	65.6±7.3	65.9±10.6^a	0.907
BMI (kg/m^2)	25.2±2.6	25.8±3.4^a	0.780
Hemoglobin (g/dL)	13.9±1.1	14.3±1.1	0.444
Platelets (×10^3/μL)	236.2±51.6	247.4±79.3	0.734
WBC (×10^3/μL)	7.139±1.776	6.505±1.449	0.436
Creatinine (mg/dL)	0.9±0.2	0.9±0.2	0.697
AST (U/L)	20.6±5.2	22.2±10.7	0.921
ALT (U/L)	20.1±7.6	23.1±16.1	0.798
γ-GTP (U/L)	19.7±9.3	22.5±7.8	0.152
IGF-1 (μIU/mL)	180.4±82.0	197.6±86.3	0.444

Mean ± SD, ^aone data point missing, HPE: human placental extract, DM: diabetes, HTN: hypertension, BMI: body mass index, WBC: white blood cell count, AST: asparate aminotransferase, ALT: alanine aminotransferase, γ-GTP: gamma glutamyl transpeptidase, IGF-1: Insulin-like growth factor-1, and P: group difference of continuous variable using Mann-Whitney test and categorical variable by Pearson Chi-square test, *by Fisher’s Exact test (d/t cells have expected count <5).