Figure 4: Effects of oral administration during 3 weeks of BuOH fraction and EtOAc fraction on COX-1 and COX-2 expression in colonic tissue of rats submitted to TNBS-induced colitis. Densitometry was made following normalization with ponceau. Results are presented as mean ± SEM ANOVA followed by Dunnett’s t-test, * and ** significantly different from nontreated.