Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 2

Research Article

Flavonoid Myricetin Modulates Receptor Activity through Activation of Channels and CaMK-II Pathway

Figure 2

CaMK-II inhibitor KN-62 blocks the effect of myricetin on receptor in PVN neurons. (a) and (b) Zolpidem increases the half-decay time of mIPSC in the PVN neurons ( , ), and this effect is totally blocked by BZ site antagonist Flumazenil. (c), Flumazenil cannot block the effect of myricetin on the decay time of mIPSC ( , ). (d) The CaMK-II inhibitor KN-62 (15 μM) could completely prevent the increase of decay time induced by myricetin ( ).

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