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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 759143, 11 pages
http://dx.doi.org/10.1155/2012/759143
Research Article

Long-Term Consumption of Platycodi Radix Ameliorates Obesity and Insulin Resistance via the Activation of AMPK Pathways

Biogeron Technology Research Group, Korea Food Research Institute, Baekhyon-dong 516, Bundang-gu, Songnam, Gyongki-do 463-746, Republic of Korea

Received 22 December 2011; Revised 10 May 2012; Accepted 17 May 2012

Academic Editor: Jae Youl Cho

Copyright © 2012 Chae Eun Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [15 citations]

The following is the list of published articles that have cited the current article.

  • Qin Zhan, Feng Zhang, Lianna Sun, Zhijun Wu, and Wansheng Chen, “Two new oleanane-type triterpenoids from platycodi radix and anti-proliferative activity in HSC-T6 Cells,” Molecules, vol. 17, no. 12, pp. 14899–14907, 2012. View at Publisher · View at Google Scholar
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  • Soo Hyun Cho, Yoosik Yoon, and Young Yang, “The Evaluation of the Body Weight Lowering Effects of Herbal Extract THI on Exercising Healthy Overweight Humans: A Randomized Double-Blind, Placebo-Controlled Trial,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–8, 2013. View at Publisher · View at Google Scholar
  • Haiyan Luan, Limin Yang, Lei Liu, Shuang Liu, Xiaolian Zhao, Hongyu Sui, Jingtao Wang, and Shuqiu Wang, “Effects of platycodins on liver complications of type 2 diabetes,” Molecular Medicine Reports, vol. 10, no. 3, pp. 1597–1603, 2014. View at Publisher · View at Google Scholar
  • Guodong Zheng, Yangyang Qiu, Qing-Feng Zhang, and Dongming Li, “Chlorogenic acid and caffeine in combination inhibit fat accumulation by regulating hepatic lipid metabolism-related enzymes in mice,” British Journal of Nutrition, vol. 112, no. 6, pp. 1034–1040, 2014. View at Publisher · View at Google Scholar
  • Yun Deng, Yali Luo, Bingjun Qian, Zhenmin Liu, Yuanrong Zheng, Xiaoyong Song, Shaojuan Lai, and Yanyun Zhao, “Antihypertensive effect of few-flower wild rice (Zizania latifolia Turcz.) in spontaneously hypertensive rats,” Food Science and Biotechnology, vol. 23, no. 2, pp. 439–444, 2014. View at Publisher · View at Google Scholar
  • Sang Woo Kim, Tae-Jun Park, Harmesh N. Chaudhari, Jae Heon Choi, Ji-Young Choi, Ye Jin Kim, Myung-Sook Choi, and Jong Won Yun, “Hepatic proteome and its network response to supplementation of an anti-obesity herbal mixture in diet-induced obese mice,” Biotechnology And Bioprocess Engineering, vol. 20, no. 4, pp. 775–793, 2015. View at Publisher · View at Google Scholar
  • Hye-Lin Kim, Jinbong Park, Hyewon Park, Yunu Jung, Dong-Hyun Youn, JongWook Kang, Mi-Young Jeong, and Jae-Young Um, “ Platycodon grandiflorum A. De Candolle Ethanolic Extract Inhibits Adipogenic Regulators in 3T3-L1 Cells and Induces Mitochondrial Biogenesis in Primary Brown Preadipocytes ,” Journal of Agricultural and Food Chemistry, pp. 150821093527006, 2015. View at Publisher · View at Google Scholar
  • Li-Juan Xiu, Da-Zhi Sun, Jian-Peng Jiao, Bing Yan, Zhi-Feng Qin, Xuan Liu, Pin-Kang Wei, and Xiao-Qiang Yue, “Anticancer effects of traditional Chinese herbs with phlegm-eliminating properties - an overview,” Journal of Ethnopharmacology, 2015. View at Publisher · View at Google Scholar
  • Guodong Zheng, Lezhen Lin, Shusheng Zhong, Qingfeng Zhang, and Dongming Li, “Effects of Puerarin on Lipid Accumulation and Metabolism in High-Fat Diet-Fed Mice,” Plos One, vol. 10, no. 3, 2015. View at Publisher · View at Google Scholar
  • Yun Hwan Kang, Kyoung Kon Kim, Tae Woo Kim, Chun Su Yang, and Myeon Choe, “Evaluation of the anti-obesity activity of Platycodon grandiflorum root and Curcuma longa root fermented with Aspergillus oryzae,” Korean Journal of Food Science and Technology, vol. 47, no. 1, pp. 111–118, 2015. View at Publisher · View at Google Scholar
  • Min-Ho Nam, Seung-Wook Lee, Hyun-Young Na, Jeong-Hwa Yoo, Sun-Ho Paik, Kwang Seok Ahn, Young-Min Ahn, Se-Young Ahn, Seung-Hoon Choi, and Byung-Cheol Lee, “Herbal Acupuncture for the Treatment of Obesity,” Journal of Acupuncture and Meridian Studies, 2015. View at Publisher · View at Google Scholar
  • Sae-Rom Yoo, Chang-Seob Seo, Hyeun-Kyoo Shin, and Soo-Jin Jeong, “Traditional Herbal Formula Oyaksungi-San Inhibits Adipogenesis in 3T3-L1 Adipocytes,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, pp. 1–10, 2015. View at Publisher · View at Google Scholar
  • Yan Zhao, Licong Yang, Zhanwang Huang, Lezhen Lin, and Guodong Zheng, “Synergistic effects of caffeine and catechins on lipid metabolism in chronically fed mice via the AMP-activated protein kinase signaling pathway,” European Journal of Nutrition, 2016. View at Publisher · View at Google Scholar
  • Hye Park, Kab-Tae Park, Edmond Park, Seung Kim, Myung Choi, Kwang-Hyeon Liu, and Choong Lee, “Mass Spectrometry-Based Metabolomic and Lipidomic Analyses of the Effects of Dietary Platycodon grandiflorum on Liver and Serum of Obese Mice under a High-Fat Diet,” Nutrients, vol. 9, no. 1, pp. 71, 2017. View at Publisher · View at Google Scholar