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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 762918, 9 pages
http://dx.doi.org/10.1155/2012/762918
Research Article

Effectiveness of the Novel Herbal Medicine, KIOM-MA, and Its Bioconversion Product, KIOM-MA128, on the Treatment of Atopic Dermatitis

1Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine (KIOM), 483 Expo-ro, Yuseong-gu, Daejeon 305-811, Republic of Korea
2College of Pharmacy, Sahmyook University, 26-21 Kongnung 2-dong, Nowon-gu, Seoul 139-742, Republic of Korea
3Regional Food Industry Research Group, Korea Food Research Institute, Sungnam 463-746, Republic of Korea

Received 23 August 2011; Accepted 10 October 2011

Academic Editor: Olumayokun A. Olajide

Copyright © 2012 Tae Ho Chung et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Y. M. Leung, M. Boguniewicz, M. D. Howell, I. Nomura, and Q. A. Hamid, “New insights into atopic dermatitis,” Journal of Clinical Investigation, vol. 113, no. 5, pp. 651–657, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. N. Novak, T. Bieber, and D. Y. Leung, “Immune mechanisms leading to atopic dermatitis,” Journal of Allergy and Clinical Immunology, vol. 112, no. 6, supplement, pp. S128–S139, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. D. Y. M. Leung, “Pathogenesis of atopic dermatitis,” Journal of Allergy and Clinical Immunology, vol. 104, no. 3, supplement, pp. S99–S108, 1999. View at Google Scholar · View at Scopus
  4. J. M. Spergel and A. S. Paller, “Atopic dermatitis and the atopic march,” Journal of Allergy and Clinical Immunology, vol. 112, no. 6, supplement, pp. S118–S127, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. P. Juto, S. Engberg, and J. Winberg, “Treatment of infantile atopic dermatitis with a strict elimination diet,” Clinical Allergy, vol. 8, no. 5, pp. 493–500, 1978. View at Google Scholar · View at Scopus
  6. R. Sidbury and J. M. Hanifin, “Systemic therapy of atopic dermatitis,” Clinical and Experimental Dermatology, vol. 25, no. 7, pp. 559–566, 2000. View at Publisher · View at Google Scholar · View at Scopus
  7. U. R. Hengge, T. Ruzicka, R. A. Schwartz, and M. J. Cork, “Adverse effects of topical glucocorticosteroids,” Journal of the American Academy of Dermatology, vol. 54, no. 1, pp. 1–15, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Furue, H. Terao, Y. Moroi et al., “Dosage and adverse effects of topical tacrolimus and steroids in daily management of atopic dermatitis,” Journal of Dermatology, vol. 31, no. 4, pp. 277–283, 2004. View at Google Scholar · View at Scopus
  9. J. M. Hanifin, “Atopic dermatitis: new therapeutic considerations,” Journal of the American Academy of Dermatology, vol. 24, no. 6, pp. 1097–1101, 1991. View at Google Scholar · View at Scopus
  10. M. P. Sheehan, M. H. A. Rustin, D. J. Atherton et al., “Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis,” The Lancet, vol. 340, no. 8810, pp. 13–17, 1992. View at Publisher · View at Google Scholar · View at Scopus
  11. T. M. Nagle, S. M. Torres, K. L. Horne, R. Grover, and M. T. Stevens, “A randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of a Chinese herbal product (P07P) for the treatment of canine atopic dermatitis,” Veterinary Dermatology, vol. 12, no. 5, pp. 265–274, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. K. L. Hon, T. F. Leung, P. C. Ng et al., “Efficacy and tolerability of a Chinese herbal medicine concoction for treatment of atopic dermatitis: a randomized, double-blind, placebo-controlled study,” British Journal of Dermatology, vol. 157, no. 2, pp. 357–363, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Yuan and Y. Lin, “Traditional Chinese medicinean approach to scientific proof and clinical validation,” Pharmacology & Therapeutics, vol. 86, no. 2, pp. 191–198, 2000. View at Publisher · View at Google Scholar · View at Scopus
  14. W. Zhang, T. Leonard, F. Bath-Hextall et al., “Chinese herbal medicine for atopic eczema,” Cochrane Database of Systematic Reviews, vol. 2, Article ID CD002291, 2005. View at Google Scholar · View at Scopus
  15. D. M. Marcus and A. P. Grollman, “Botanical medicines - The need for new regulations,” The New England Journal of Medicine, vol. 347, no. 25, pp. 2073–2076, 2002. View at Publisher · View at Google Scholar · View at Scopus
  16. J. B. Calixto, “Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents),” Brazilian Journal of Medical and Biological Research, vol. 33, no. 2, pp. 179–189, 2000. View at Google Scholar · View at Scopus
  17. S. S. Joo, T. J. Won, S. Y. Nam et al., “Therapeutic advantages of medicinal herbs fermented with Lactobacillus plantarum, in topical application and its activities on atopic dermatitis,” Phytotherapy Research, vol. 23, no. 7, pp. 913–919, 2009. View at Google Scholar
  18. J. D. van der Merwe, E. Joubert, E. S. Richards et al., “A comparative study on the antimutagenic properties of aqueous extracts of Aspalathus linearis (rooibos), different Cyclopia spp. (honeybush) and Camellia sinensis teas,” Mutation Research, vol. 611, no. 1-2, pp. 42–53, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Chun, G. M. Kim, K. W. Lee et al., “Conversion of isoflavone glucosides to aglycones in soymilk by fermentation with lactic acid bacteria,” Journal of Food Science, vol. 72, no. 2, pp. M39–M44, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Saeedi, K. Morteza-Semnani, and M. R. Ghoreishi, “The treatment of atopic dermatitis with licorice gel,” Journal of Dermatological Treatment, vol. 14, no. 3, pp. 153–157, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. J. H. Kim, J. H. Jeong, S. T. Jeon et al., “Decursin inhibits induction of inflammatory mediators by blocking nuclear factor-κB activation in macrophages,” Molecular Pharmacology, vol. 69, no. 6, pp. 1783–1790, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. T. Yoon, D. Y. Lee, A. Y. Lee, G. Choi, B. K. Choo, and H. K. Kim, “Anti-inflammatory effects of Glehnia littoralis extract in acute and chronic cutaneous inflammation,” Immunopharmacology and Immunotoxicology, vol. 32, no. 4, pp. 663–670, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. W. He, H. Sun, B. Yang, D. Zhang, and D. Kabelitz, “Immunoregulatory effects of the Herba Epimediia glycoside icariin,” Arzneimittel-Forschung, vol. 45, no. 8, pp. 910–913, 1995. View at Google Scholar · View at Scopus
  24. W. J. Kim, M. Y. Lee, J. H. Kim, K. Suk, and W. H. Lee, “Decursinol angelate blocks transmigration and inflammatory activation of cancer cells through inhibition of PI3K, ERK and NF-κB activation,” Cancer Letters, vol. 296, no. 1, pp. 35–42, 2010. View at Publisher · View at Google Scholar · View at Scopus