Pharmacokinetics of Ganoderic Acids A and F after Oral Administration of Ling Zhi Preparation in Healthy Male Volunteers

Table 1

The demographic characteristics and clinical laboratory data of 12 subjects enrolled in the study.

Parameters	Mean ± SD	Range	Normal values
Age (y)	26.83±4.86	20–33
Weight (kg)	58.38±7.29	48.5–74.0
Height (m)	1.69±0.06	1.60–1.78
BMI (kg/m^2)	20.51±1.97	18.25–23.36	18–25
Laboratory data
Hemoglobin (g/L)	145.50±6.49	130–157	130–180
Hematocrit (L/L)	0.45±0.02	0.43–0.48	0.40–0.54
WBC (×10^9/L)	7.93±1.83	5.6–11.0	4.4–11.0
Platelets on smear	Adequate	—	Adequate
BUN (mg/dL)	13.17±1.95	10–17	8.4–21
Creatinine (mg/dL)	1.08±0.11	0.9–1.3	0.8–1.3
SGOT (U/L)	21.58±4.54	16–30	0–37
SGPT (U/L)	23.50±9.13	13–39	0–41
ALP (U/L)	47.50±11.02	30–64	53–128
Total bilirubin (mg/dL)	0.42±0.23	0.2–0.9	0.1–1.2

BMI: body mass index; WBC: white blood cell; BUN: blood urea nitrogen; SGOT: serum glutamic oxaloacetic transaminase; SGPT: serum glutamic pyruvic transaminase; ALP: alkaline phosphatase.