Myricetin Increases Hepatic Peroxisome Proliferator-Activated Receptor α Protein Expression and Decreases Plasma Lipids and Adiposity in Rats
Figure 3
Histopathological findings in epididymal white adipose tissue of HFD-fed rats receiving 8-week treatment with myricetin or fenofibrate. Rats not receiving any treatment were given the same volume of vehicle (distilled water) used to dissolve the test medications. (a) Photomicrographs were taken at a magnification of ×400. Photomicrographs are of tissues isolated from vehicle-treated RCD-fed rats (vehicle-RCD), vehicle-treated HFD-fed rats (vehicle-HFD), myricetin- (300 mg kg−1 per day) treated HFD-fed rats (myricetin-HFD), or fenofibrate- (100 mg kg−1 per day) treated HFD-fed rats (fenofibrate-HFD). (b) The size of adipocytes in a fixed area (1,000,000 μm2) was measured. All values are expressed as mean with SEM ( per group) in each column. a compared to the values of vehicle-treated HFD-fed group.
