Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 4

Research Article

In Vivo Anti-Influenza Virus Activity of Japanese Herbal (Kampo) Medicine, “Shahakusan,” and Its Possible Mode of Action

Figure 4

Effect of SHS on the proliferation of influenza virus in the nasal cavity of upper respiratory tract infected mice. BALB/c mice were administered orally with water, SHS or oseltamivir from 7 days before to 4 days p.i. (−7 d to 4 d), one day before to 4 days p.i. (−1 d to 4 d), or 2 hours p.i. to 4 days p.i. (2 h to 4 d) as shown in Figure 2(a). The infectious virus titers in NLF of influenza virus infected mice were estimated at 5 day p.i. with plaque assay. Values represent means ± S.E. ( ).