Research Article
Hepatoprotective and Antioxidative Activities of Cornus officinalis against Acetaminophen-Induced Hepatotoxicity in Mice
Figure 5
Protective effect of ECO on APAP-induced hepatotoxicity: HO-1 and liver index. Control, D.W treated/PBS injected; APAP, D.W treated/APAP 200 mg/kg injected; Silymarin, silymarin 200 mg/kg treated/APAP 200 mg/kg injected; ECO 100, ECO 100 mg/kg treated/APAP 200 mg/kg injected, ECO 250, ECO 250 mg/kg treated/APAP 200 mg/kg injected, ECO 500, ECO 500 mg/kg treated/APAP 200 mg/kg injected, ECO only, ECO 500 mg treated/PBS injected. Values are expressed as means ± SEM ( or 9 mice/group). *Significant difference from Control, P < 0.05; †significant difference from APAP, P < 0.05.