Inhibition of Activity of GABA Transporter GAT1 by 𝜹-Opioid Receptor

Table 1

Parameters of (1) fitted to the data shown in Figure 5(a).

	𝑄max (nC)	𝐸1/2 (mV)	𝑧𝑓	𝑄max/𝑧𝑓 (𝑁 per oocyte)	𝑘^∗1 (s^−1)	𝑎1 (mV^−1)	𝑘^∗2 (s^−1)	𝑎2 (mV^−1)
GAT1	73.3	−32.3	1.2	6.1 × 10^11	6.8	85.6	7.8	39.5
GAT1 + 𝛿OR	49.4			4.1 × 10^11	3.3		5.4
GAT1 + 𝛿OR (1 𝜇M DPDPE)	39.7			3.3 × 10^11