Curative Effects of Oleanolic Acid on Formed Hypertrophic Scars in the Rabbit Ear Model

Figure 2

Effects of OA on TGF-𝛽₁ protein expression in the scar tissue. The protein expression level of TGF-𝛽₁ was significantly increased in the control group of scar tissue but evidently decreased following administration of OA (2.5%, 5%, and 10%) for 28 consecutive days. ^ΔΔ𝑃<0.01 compared with the normal group; ^∗𝑃<0.05 and ^∗∗𝑃<0.01 compared with the control group. Data are expressed as the mean ± SD. 𝑛=3.