Liuwei Dihuang Lowers Body Weight and Improves Insulin and Leptin Sensitivity in Obese Rats
Figure 1
LWDH significantly lowered body weight in obese rats. OR: obesity-resistant normal control; OP: obesity-prone positive control; T1A, T1B, and T1C represent the 3 obesity-prone groups treated by twice daily oral gavage with total daily dosages of 500, 1500, or 3500 mg/kg BW of the LWDH herbal formulation, respectively. All animals were fed a high-fat diet (AIN-93G diet modified to contain 60% energy from fat (lard : sunflower oil (96 : 4, wt/wt)). Data were analyzed by one-way ANOVA. Differences between treatment means were determined by pair-wise comparisons using the least squares means test, with indicating statistical significance. Results are presented as mean values with their standard errors (). *Differed significantly from OP ().
