Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-<i>κ</i>B Inhibition

<table>Liver and kidney histology of control and dentatin-treated animals. Wildtype rats were treated intraperitoneally with vehicle (CMC) only or with dentatin at concentrations 100 or 1000 mg/kg for 14 days. Liver and kidney were fixed, sectioned, and stained with Hematoxylin and Eosin. No significant signs of toxicity were observed in the liver and kidney histological sections of treated rats. Magnification 20x.</table>

Evidence-Based Complementary and Alternative Medicine

fig11

Figure 11

Figure 11: Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-<i>κ</i>B Inhibition 

Figure 11 | Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition 