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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 856029, 15 pages
http://dx.doi.org/10.1155/2012/856029
Research Article

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition

1Cancer Research Laboratory, Institute of Bioscience, University Putra Malaysia, 43400 Serdang, Malaysia
2Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
3Department of Molecular Immunology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
4Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 Serdang, Malaysia
5Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
6Medical Research Center, Faculty of Medicine, Jazan University, Jazan 82621, Saudi Arabia

Received 17 March 2012; Revised 28 August 2012; Accepted 28 August 2012

Academic Editor: Paolo Bellavite

Copyright © 2012 Ismail Adam Arbab et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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