Effect of capsaicin application on current-voltage curves. (a) Membrane current in oocytes injected with TRPV1-cRNA. Large open circles before, filled squares during, and small open circles after application of 500 nM capsaicin. (b) Capsaicine-induced current in uninjected oocytes (open circles) and cRNA-injected oocytes (filled squares). All data are averages from 8 experiments (SEM).