Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 5

Research Article

Melanogenesis Inhibitor(s) from Phyla nodiflora Extract

Figure 5

Methanolic extract of Phyla nodiflora degrades the MITF protein by activating phosphorylation of mitogen-activated protein kinases (MAPKs), (a) phospho-extracellular signal-regulated kinase (ERK), (b) phosphor-c-Jun N-terminal kinase (p-JNK), and (c) p-p38. The different superscript letters indicate significant difference at using ANOVA followed with Tukey’s post-hoc test. *Significantly different from 0 h.