Melanogenesis Inhibitor(s) from Phyla nodiflora Extract
Methanolic extract of P. nodiflora decreased the melanin production induced by mitogen-activated protein kinase (MAPK)-specific inhibitors. The different superscript letters indicate significant difference at using ANOVA followed with Tukey’s post-hoc test. #Significant different from control; *U0126, SB202190, SP600125, and treatment with a combination of all 3 inhibitors compared to control; §PNM treated with SB202190 inhibitor compared to SB202190 only. ⋆PNM treated with U0126 inhibitor compared to U0126 only. &PNM treated with a combination of all 3 inhibitors compared to treatment with all 3 inhibitors.