Research Article

Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial

Table 7

Adverse events observed in CRC patients in adjuvant/palliative chemotherapy with FOLFOX4 ( ).

After 1 chemotherapy cycle (FOLFOX4)After 6 chemotherapy cycles (FOLFOX4)
Grade refers to the severity of the AE*Grade refers to the severity of the AE
0123401234

Hemoglobin82.912.24.90076.917.92.600
Leukocytes (total WBC)97.62.400074.45.115.45.10
Neutrophils/granulocytes85.47.304.92.448.712.810.317.97.7
Lymphocytes95.104.90092.307.700
Platelets97.602.40084.610.35.100
Weight loss82.99.82.44.9092.302.65.10
Hyperglycemia97.6002.4087.207.75.10
γ-glutamyl transpeptidase100000089.810.2000
Alkaline phosphatase100000084.615.4000
Neuropathy: sensory100000094,905.100
Infection with Grade 3 or 4 neutrophils100000097.402.600
Diarrhea100x00092.3x7.700

Values expressed as % of the patients who had AE. *Grade refers to the severity of the AE: grade 1 = mild AE; grade 2 = moderate AE; grade 3 = severe AE; grade 4 = life-threatening or disabling AE; grade 5 = death related to an AE [22].