Study of the Effects of Monacolin K and Other Constituents of Red Yeast Rice on Obesity, Insulin-Resistance, Hyperlipidemia, and Nonalcoholic Steatohepatitis Using a Mouse Model of Metabolic Syndrome

Table 3

Body weight, organ weight, and serum parameters at 24 weeks of age in all experimental groups. All mice were administered MSG at birth. Variables are expressed as mean ± SEM.

Parameters	C	RYR-C	RYR-M
Body weight (g)	56.3 ± 1.1	51.8 ± 1.6	53.0 ± 2.0
Liver to body weight ratio (%)	4.8 ± 0.4	3.9 ± 0.3	4.1 ± 0.2
Visceral fat to body weight ratio (%)	2.9 ± 0.5	3.6 ± 0.3	3.0 ± 0.2
Total cholesterol (mg/dL)	137.1 ± 11.8	107.3 ± 7.8	116.5 ± 16.4
LDL cholesterol (mg/dL)	22.3 ± 3.5	16.2 ± 2.7	22.1 ± 5.3
TG (mg/dL)	48.2 ± 4.5	80.2 ± 5.1**	58.1 ± 5.3^†
NEFA (mEq/L)	1.1 ± 0.1	1.0 ± 0.1	1.1 ± 0.1
AST (IU/L)	53.4 ± 7.0	41.4 ± 8.0	53.7 ± 9.4
ALT (IU/L)	28.1 ± 6.6	20.1 ± 6.1	29.8 ± 5.8

**Versus C P < 0.01, ^†versus RYR-C P < 0.05.