Hesperidin-3′-O-Methylether Is More Potent than Hesperidin in Phosphodiesterase Inhibition and Suppression of Ovalbumin-Induced Airway Hyperresponsiveness
Figure 7
Effects of subcutaneously administered hesperidin and hesperidin-3′-O-methylether (a) and Ro 20-1724 (b) on the duration of xylazine (10 mg/kg, i.p.)/ketamine (70 mg/kg, i.p.)-induced anesthesia in mice. Ro 20-1724 was administered 0.25 h and hesperidin and hesperidin-3′-O-methylether 1 h before anesthesia. *, ***, compared to the vehicle (control). Each value represents the mean ± SEM. The number of mice in each group was 10.
