Phyllanthus urinaria Induces Apoptosis in Human Osteosarcoma 143B Cells via Activation of Fas/FasL- and Mitochondria-Mediated Pathways

Figure 6

Caspase inhibitors decreased apoptosis inducing by P. urinaria in 143B cells. The representative Western blot analyses demonstrating the effects of the caspase-3, 8, 9 inhibitors including Z-DEVD-FMK, Z-IETD-FMK, Z-LEHD-FMK and the pan-caspase inhibitor Z-VAD-FMK on caspase-3 expression in 143B cells treated without or with 2 mg/mL P. urinaria. The Western blot data represent one of the three independent experiments.