The Effects of Jiang-Zhi-Ning and Its Main Components on Cholesterol Metabolism

Table 3

The effects of nuciferine treatment on cholesterol metabolism in liver cells (mRNA analysis).

Treatment	LDL-R	HMG-CoAR	CYP7A1	ACAT2
No nuciferine	1	1	1	1
Nuciferine: low dose	1.86±0.84 **	2.18±0.26 **	0.94±0.17	0.97±0.24
Nuciferine: medium dose	2.95±0.25 **	2.58±0.14 **	0.93±0.26	0.95±0.28
Nuciferine: high dose	3.57±1.01 **	2.96±0.25 **	1.15±0.31	0.78±0.19 **
Atorvastatin	5.83±0.19 **	6.58±0.28 **	1.29±0.12 *	0.49±0.33 **

Note: comparison with no-drug control group, *𝑃<0.05, **𝑃<0.01.