Research Article

Resveratrol Produces Neurotrophic Effects on Cultured Dopaminergic Neurons through Prompting Astroglial BDNF and GDNF Release

Figure 3

Resveratrol increased BDNF and GDNF production in the culture medium. The production of BDNF and GDNF in the supernatant of primary neuron-glia cultures after resveratrol treatment for 48 h was measured by ELISA (a). Twelve, 24, 36, 48, 72, and 96 h after resveratrol (100  M) treatment on the first day, the release of BDNF and GDNF in the culture medium was detected by ELISA (b). Results were the mean ± SEM from three independent experiments performed in triplicate. compared with the control cultures.
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(a)
937605.fig.003b
(b)