Endothelium/Nitric Oxide Mediates the Vasorelaxant and Antihypertensive Effects of the Aqueous Extract from the Stem Bark of Mammea africana Sabine (Guttiferae)

Figure 7

Effect of chronic administration of the aqueous extract of Mammea africana (200 mg/kg/d) and captopril (20 mg/kg/d) on systolic blood pressure (SBP) of L-NAME (40 mg/kg/d) hypertensive rats. Arrow indicates the time when the aqueous extract and captopril were introduced. Data represent the mean ± SEM, 𝑛=5. ^a𝑃<0.05; ^b𝑃<0.01; ^c𝑃<0.001 compared to control. ^𝛽𝑃<0.01; ^𝛾𝑃<0.001 compared to L-NAME.