Hepatoprotective Effects of Total Triterpenoids and Total Flavonoids from Vitis vinifera L against Immunological Liver Injury in Mice

Table 1

Effects of VTT and VTF on liver index, spleen index, and homogenate ALT and AST activities in ILI mice.

Group	𝑛	Dose (mg/kg)	ALT (U/g prot)	AST (U/g prot)	Liver index (%)	Spleen index (%)
Normal	12		631.78±81.08	215.73±26.19	0.5564±0.0577	0.0298±0.0083
BCG + LPS	10		242.75±63.15^a	51.59±12.03^a	0.6979±0.1238^a	0.0843±0.0247^a
BCG + LPS + DDB	12	200	519.57±154.05^b	90.61±13.30^b	0.5466±0.0628^b	0.0502±0.0101^b
BCG + LPS + VTT	11	50	366.56±83.77^b	66.74±18.56	0.5810±0.0655^b	0.0619±0.0171^b
	11	150	499.62±96.11^b	81.86±14.86^b	0.5801±0.0725^b	0.0646±0.0116^b
	12	300	507.19±138.13^b	96.69±33.88^b	0.5871±0.0556^b	0.0585±0.0160^b
BCG + LPS + VTF	10	50	408.70±57.85^b	63.63±22.47	0.5524±0.0908^b	0.0581±0.0213^b
	12	150	489.24±130.33^b	79.97±11.54^b	0.5457±0.0557^b	0.0539±0.0113^b
	12	300	502.85±129.12^b	85.60±18.40^b	0.6090±0.0643^b	0.0552±0.0092^b

Values are the mean ± S.D. ^a𝑃<0.01, compared with normal group; ^b𝑃<0.01, compared with ILI model group.