Research Article

Diosgenin Induces Apoptosis in HepG2 Cells through Generation of Reactive Oxygen Species and Mitochondrial Pathway

Figure 6

Effects of diosgenin on MAPK (a) and ASK1 (b). Cells were treated with varying concentrations of diosgenin (20–40 μM) for 24 h. Total cell lysates were analyzed by immunoblotting with antibody against phospho-p38, p38, phospho-JNK, JNK, phosphoASK1, and ASK1.
981675.fig.006a
(a)
981675.fig.006b
(b)