Renal Protective Effect of Xiao-Chai-Hu-Tang on Diabetic Nephropathy of Type 1-Diabetic Mice
Figure 2
Effects of XCHT on kidney hypertrophy of normal or STZ-diabetic mice after a 4-week XCHT (200 mg/kg) or vehicle (Veh) treatment. (a) The kidney/body weight ratio. Values (mean ± SD) were collected from 6 mice for each test group. (b) Representative photomicrographs (original magnification, 200x) of PAS-stained kidney sections from STZ-diabetic mice receiving 4 weeks of XCHT or vehicle treatment; (A) normal mice treated with vehicle, (B) STZ-diabetic mice treated with vehicle, and (C) STZ-diabetic mice treated with XCHT. (c) Expansion of the glomerular matrix was scored as described in the text, and an average value was obtained from analyses of 30 glomeruli in each mouse kidney. #values of STZ-diabetic mice compared to that of the normal mice. * values of XCHT-treated STZ-diabetic mice compared to values from vehicle-treated STZ-diabetic mice.
