Inhibition of Neurotoxic Secretory Phospholipases A2 Enzymatic, Edematogenic, and Myotoxic Activities by Harpalycin 2, an Isoflavone Isolated from Harpalyce brasiliana Benth
Figure 6
(a) Multiple sequence alignment of PrTX-III, Cdt F15, Naja and Apis, with the PDB ID: 1GMZ, 2QOG, 1PSH and 1POC, respectively. ClustalX was used with default setup. (b) Structure alignment of the PLA2 (cartoon model) with their respective docking solutions for harpalycin 2 (stick model): PrTX-III (green), Cdt F15 (red), and Naja (blue). Figure generated using PyMOL [28].
