Table 2: Effect of petal extracts of N.  nucifera on central receptors.

Name of the test itemSolventConcentrationRLU (Mean ± SD)
5HT2CMC4RMCHR1CNR2

NegativeNA NANA
DMSO 0.1% NANA
N.  nucifera methanol extract DMSO10  g/mL (NS) (NS)
N.  nucifera successive water extractDMEM10  g/mL (NS) (NS) (NS)
Agonist AL-34662
(reference standard)
DMSO50 nm* NANANA
Agonist melanotan II acetate salt
(reference standard)
DMSO950 nm*NA NANA
Agonist CP 55,940 DMSO4.5 nm1NANANA
Agonist MCH DMSO62.5 nm1NANA NA
Antagonist AM630
(reference standard)
DMSO173.2 nm*NANANA
Antagonist GW-803430
(reference standard)
DMSO18.1 nm*NANA NA

RLU: relative luminescence units; NA: not applicable; *indicates a concentration at which maximum response of reference controls was observed; 1indicates EC80 concentration of agonist against which N.  nucifera petal extracts/reference controls were evaluated for their antagonistic potential.
.
NS: not significant.