Attenuation of Proinflammatory Responses by S-[6]-Gingerol via Inhibition of ROS/NF-Kappa B/COX2 Activation in HuH7 Cells
Figure 2
S-[6]-Gingerol decreases IL1β-induced inflammatory factors expression in HuH7 cell. HuH7 cells were pretreated with 100 μM S-[6]-gingerol (G) or DMSO (vehicle control) for 6 h then stimulated with IL1β (8 ng/mL) for 3 h. The mRNA levels of IL6 (a), IL8 (b), and SAA1 (c) were measured using RT-qPCR, normalised to B2M. Results are expressed as mean SEM of 3 independent experiments, relative to DMSO controls. versus DMSO vehicle control; versus IL1β treatment.
