Table of Contents Author Guidelines Submit a Manuscript
Retracted

Evidence-Based Complementary and Alternative Medicine has retracted this article. Figure 5(a)-(iv) is reused from Figure 15A-II in an article by the same authors, Salama et al. [2].

An institutional investigation by the University of Malaya found there was no system to index and file data and images to avoid mislabeling and mishandling, which led to errors and duplication of research data. The authors did not thoroughly check the manuscript before submission.

The authors said that to save time, animal experiments were conducted on both plants at the same time and to cut costs, immunohistochemistry staining was performed at the same time on the liver tissues collected from all animals of both experiments using one kit and one protocol. In addition, the results of both experiments were very close and so they mixed up images between the two experiments.

View the full Retraction here.

References

  1. S. M. Salama, M. A. Abdulla, A. S. Alrashdi, and A. H. A. Hadi, “Mechanism of hepatoprotective effect of Boesenbergia rotunda in thioacetamide-induced liver damage in rats,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 157456, 13 pages, 2013.
  2. S. M. Salama, M. A. Abdulla, A. S. AlRashdi, S. Ismail, S. S. Alkiyumi, and S. Golbabapour, “Hepatoprotective effect of ethanolic extract of Curcuma longa on thioacetamide induced liver cirrhosis in rats,” BMC Complementary and Alternative Medicine, vol. 13, article no. 56, 2013.
Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 157456, 13 pages
http://dx.doi.org/10.1155/2013/157456
Research Article

Mechanism of Hepatoprotective Effect of Boesenbergia rotunda in Thioacetamide-Induced Liver Damage in Rats

1Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
2Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia

Received 23 March 2013; Revised 2 June 2013; Accepted 17 June 2013

Academic Editor: Sedigheh Asgary

Copyright © 2013 Suzy M. Salama et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [27 citations]

The following is the list of published articles that have cited the current article.

  • Suzy M. Salama, Ahmed S. AlRashdi, Mahmood A. Abdulla, Pouya Hassandarvish, and Mehmet Bilgen, “Protective activity of Panduratin A against Thioacetamide-induced oxidative damage: demonstration with in vitro experiments using WRL-68 liver cell line,” Bmc Complementary and Alternative Medicine, vol. 13, 2013. View at Publisher · View at Google Scholar
  • Atef M. Al-Attar, and Nessreen A. Shawush, “Influence of olive and rosemary leaves extracts on chemically induced liver cirrhosis in male rats,” Saudi Journal of Biological Sciences, 2014. View at Publisher · View at Google Scholar
  • Dalia O. Saleh, Gehad A. Raheem Abdel Jaleel, Sally A. El-Awdan, Fatma Oraby, and Manal Badawi, “Thioacetamide-induced liver injury: protective role of genistein,” Canadian Journal of Physiology and Pharmacology, pp. 1–9, 2014. View at Publisher · View at Google Scholar
  • Noraziah Nordin, Suzy Munir Salama, Shahram Golbabapour, Maryam Hajrezaie, Pouya Hassandarvish, Behnam Kamalidehghan, Nazia Abdul Majid, Najihah Mohd Hashim, Hanita Omar, Mehran Fadaienasab, Hamed Karimian, Hairin Taha, Hapipah Mohd Ali, and Mahmood Ameen Abdulla, “Anti-Ulcerogenic Effect of Methanolic Extracts from Enicosanthellum pulchrum (King) Heusden against Ethanol-Induced Acute Gastric Lesion in Animal Models,” Plos One, vol. 9, no. 11, 2014. View at Publisher · View at Google Scholar
  • Dewi Ratna Sulistina, Retty Ratnawati, and I Wayan Arsana Wiyasa, “Rhodamine B increases hypothalamic cell apoptosis and disrupts hormonal balance in rats,” Asian Pacific Journal of Reproduction, vol. 3, no. 3, pp. 180–183, 2014. View at Publisher · View at Google Scholar
  • Jonathan Arauz, Yadira Rivera-Espinoza, Mineko Shibayama, Liliana Favari, Rosa Elena Flores-Beltran, and Pablo Muriel, “Nicotinic acid prevents experimental liver fibrosis by attenuating the prooxidant process,” International Immunopharmacology, vol. 28, no. 1, pp. 244–251, 2015. View at Publisher · View at Google Scholar
  • Ibrahim Halil Bahcecioglu, Murat Ispiroglu, Mehmet Tuzcu, Cemal Orhan, Mustafa Ulas, Ulvi Demirel, Mehmet Yalniz, Ibrahim H. Özercan, Necip Ilhan, and Kazim Sahin, “Pistacia Terebinthus Coffee Protects against Thioacetamide-Induced Liver Injury in Rats,” Acta Medica (Hradec Kralove, Czech Republic), vol. 58, no. 2, pp. 56–61, 2015. View at Publisher · View at Google Scholar
  • Ratna Feti Wulandari, Endang Sri Wahyuni, Sutrisno Sutrisno, RR Catur Leny Wulandari, Dwi Wahyu Wulan Sulistyowati, Yuyun Yueniwati, and Sanarto Santoso, “Effect of genistein on proinflammatory cytokines and estrogen receptor-β in mice model of endometriosis,” Asian Pacific Journal of Reproduction, vol. 4, no. 2, pp. 96–99, 2015. View at Publisher · View at Google Scholar
  • Kornkanok Tangjitman, Chalobol Wongsawad, Kaweesin Kamwong, Treetip Sukkho, and Chusie Trisonthi, “Ethnomedicinal plants used for digestive system disorders by the Karen of northern Thailand,” Journal of Ethnobiology and Ethnomedicine, vol. 11, no. 1, 2015. View at Publisher · View at Google Scholar
  • Peter Surai, “Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives,” Antioxidants, vol. 4, no. 1, pp. 204–247, 2015. View at Publisher · View at Google Scholar
  • Alyaa Hessin, Rehab Hegazy, Azza Hassan, Nemat Yassin, and Sanaa Kenawy, “Lactoferrin enhanced apoptosis and protected against thioacetamide-induced liver fibrosis in rats,” Macedonian Journal of Medical Sciences, vol. 3, no. 2, pp. 195–201, 2015. View at Publisher · View at Google Scholar
  • Muhammad Jahangir Hossen, Seung Cheol Kim, Young-Jin Son, Kwang-Soo Baek, Eunji Kim, Woo Seok Yang, Deok Jeong, Jae Gwang Park, Han Gyung Kim, Woo-Jae Chung, Keejung Yoon, Chongsuk Ryou, Sang Yeol Lee, Jong-Hoon Kim, and Jae Youl Cho, “ AP-1-Targeting Anti-Inflammatory Activity of the Methanolic Extract of Persicaria chinensis ,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, pp. 1–11, 2015. View at Publisher · View at Google Scholar
  • Shahira M. Ezzat, Maha M. Salama, Sayed H. Seif el-Din, Samira Saleh, Naglaa M. El-Lakkany, Olfat A. Hammam, Maha B. Salem, and Sanaa S. Botros, “ Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces ,” Pharmaceutical Biology, pp. 1–10, 2016. View at Publisher · View at Google Scholar
  • A. A. El-Mansy, S. A. Mazroa, W. S. Hamed, A. H. Yaseen, and E. A. El-Mohandes, “Histological and immunohistochemical effects of Curcuma longa on activation of rat hepatic stellate cells after cadmium induced hepatotoxicity,” Biotechnic & Histochemistry, vol. 91, no. 3, pp. 170–181, 2016. View at Publisher · View at Google Scholar
  • T. K. Lim, and T. K. Lim, “Boesenbergia rotunda,” Edible Medicinal and Non-Medicinal Plants, pp. 214–232, 2016. View at Publisher · View at Google Scholar
  • Sahar El-Sayed Elswefy, Fatma Rizk Abdallah, Hebatallah Husseini Atteia, Alaa Samir Wahba, and Rehab Abdallah Hasan, “Inflammation, oxidative stress and apoptosis cascade implication in bisphenol A-induced liver fibrosis in male rats,” International Journal of Experimental Pathology, 2016. View at Publisher · View at Google Scholar
  • Tong Kwee Limpp. 1–690, 2016. View at Publisher · View at Google Scholar
  • Aziza B. Shalby, Mohamed Diaa Abd El-Maksoud, Ahmed E. Abdel Moneim, and Hanaa H. Ahmed, “Antifibrotic candidates of Selenium nanoparticles and selenium in the experimental model,” Journal of Applied Pharmaceutical Science, vol. 7, no. 9, pp. 191–198, 2017. View at Publisher · View at Google Scholar
  • Kholoud Alaa El-Mihi, Hany Ibrahim Kenawy, Amro El-Karef, Nehal Mohsen Elsherbiny, and Laila Ahmed Eissa, “Naringin attenuates thioacetamide-induced liver fibrosis in rats through modulation of the PI3K/Akt pathway,” Life Sciences, 2017. View at Publisher · View at Google Scholar
  • Alyaa Hessin, Rehab Rehab Hegazy, Nemat Zakaria Yassin, Sanaa Abdel-Baky Kenawy, and Azza Ahmed Hassan, “Resveratrol prevents liver fibrosis via two possible pathways: Modulation of alpha fetoprotein transcriptional levels and normalization of protein kinase C responses,” Indian Journal of Pharmacology, vol. 49, no. 4, pp. 282–289, 2017. View at Publisher · View at Google Scholar
  • Oranun Ongwisespaiboon, and Wannee Jiraungkoorskul, “Fingerroot, Boesenbergia rotunda and its aphrodisiac activity,” Pharmacognosy Reviews, vol. 11, no. 21, pp. 27–30, 2017. View at Publisher · View at Google Scholar
  • Fui-Ling Voon, Mohd Roslan Sulaiman, Enoch Kumar Perimal, Muhammad Nadeem Akhtar, Mohamad Fauzi Idris, Ahmad Akira, Daud Ahmad Israf, and Lee Ming-Tatt, “Cardamonin (2′,4′-dihydroxy-6′-methoxychalcone) isolated from Boesenbergia rotunda (L.) Mansf. inhibits CFA-induced rheumatoid arthritis in rats,” European Journal of Pharmacology, vol. 794, pp. 127–134, 2017. View at Publisher · View at Google Scholar
  • Fatma H. Rizk, Naglaa I. Sarhan, Nema A. Soliman, Marwa A. A. Ibrahim, Marwa Abd-Elsalam, and Sherief Abd-Elsalam, “Heat shock protein 47 as indispensible participant in liver fibrosis: Possible protective effect of lactoferrin,” IUBMB Life, 2018. View at Publisher · View at Google Scholar
  • Suzy M. Salama, Ibrahim Abdel Aziz Ibrahim, Naiyer Shahzad, Saeed Al-Ghamdi, Nahla Ayoub, Ahmed Salim AlRashdi, Mahmood Ameen Abdulla, Nur'Ain Salehen, and Mehmet Bilgen, “ Hepatoprotectivity of Panduratin A against liver damage: In vivo demonstration with a rat model of cirrhosis induced by thioacetamide ,” Apmis, 2018. View at Publisher · View at Google Scholar
  • Kumeshini Sukalingam, Kumar Ganesan, and Baojun Xu, “Protective Effect of Aqueous Extract from the Leaves of Justicia tranquebariesis against Thioacetamide-Induced Oxidative Stress and Hepatic Fibrosis in Rats,” Antioxidants, vol. 7, no. 7, pp. 78, 2018. View at Publisher · View at Google Scholar
  • Varinder Kaur, Manish Kumar, Ajay Kumar, Kamaldeep Kaur, Varinderpal Singh Dhillon, and Satwinderjeet Kaur, “Pharmacotherapeutic potential of phytochemicals: Implications in cancer chemoprevention and future perspectives,” Biomedicine & Pharmacotherapy, vol. 97, pp. 564–586, 2018. View at Publisher · View at Google Scholar
  • Xiao-jie Mi, Jin-gang Hou, Shuang Jiang, Zhi Liu, Shan Tang, Xiang-xiang Liu, Ying-ping Wang, Chen Chen, Zi Wang, and Wei Li, “Maltol Mitigates Thioacetamide-induced Liver Fibrosis through TGF-β1-mediated Activation of PI3K/Akt Signaling Pathway,” Journal of Agricultural and Food Chemistry, 2019. View at Publisher · View at Google Scholar