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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 159392, 9 pages
Review Article

Important Developments in Romanian Propolis Research

Faculty of Animal Breeding and Biotechnology, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Mănăştur Street 3-5, 400372 Cluj-Napoca, Romania

Received 9 January 2013; Revised 8 May 2013; Accepted 16 May 2013

Academic Editor: Vassya Bankova

Copyright © 2013 Liviu Al Mărghitaş et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The most important developments in propolis analysis and pharmacological properties are discussed. In order to help in the Romanian propolis standardization, different methodologies for chemical composition analysis (UV-VIS, HP-TLC, and HPLC-DAD) are reviewed using new approaches and software (fuzzy divisive hierarchical clustering approach and ChromQuest software) and compared with international studies made until now in propolis research. Practical applications of Romanian propolis in medicinal therapy and cosmetics are reviewed, and quality criteria for further standardization are proposed.