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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 160168, 10 pages
Research Article

Expression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts

1College of Basic Medicine and School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210029, China
2Zhejiang California International Nanosystems Institute, Zhejiang University, Hangzhou 310058, China
3School of Chinese Medicine, Hong Kong Baptist University, Hong Kong
4Department of Pharmacology and Winship Cancer Institute, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA

Received 28 March 2013; Revised 8 July 2013; Accepted 17 July 2013

Academic Editor: Aiping Lu

Copyright © 2013 Luyu Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

We identified 40 peptides (corresponding to 36 proteins) and 178 peptides (corresponding to 84 proteins) that are differentially expressed in the comparison between the MOCK and the DDP group, and the comparison between the MOCK and the JIN group. We found that, the expression of HSP90AA1 and HSPA1B are two most significantly reduced proteins after the JIN group treatment compared with the MOCK group. HSPA1B is also significantly reduced in the DDP group compared with the MOCK group.

  1. Supplementary material