Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats
Figure 2
The plasma concentration-time profiles of baicalin. Rats received intravenous administration of baicalin (a) at a single dose of 0.225 or 0.45 g/kg (); (b) at a dose of 0.90 g/kg once for 1 day and the same dose for 7 days (). The results are the mean SD of the indicated number of rats.